GRANOCYTE 33,6 263 g

The name of this medicine is Granocyte powder and solvent for solution for injection/infusion (referred to as Granocyte in this leaflet). Granocyte contains the active substance lenograstim. It belongs to a group of drugs called cytokines. Granocyte works by helping your body form more blood cells that fight infection: These red blood cells are made in your bone marrow Granocyte stimulates your bone marrow to produce more cells called "blood precursor cells" helps these young cells develop into fully functional blood cells specifically, it helps produce more neutrophils, a type of white blood cell. Neutrophils are important in the fight against infections.

Preparation of the reconstituted solution Syringes:

Aseptically (i.e., hands thoroughly washed with soap and dried) add the contents of a pre-filled syringe to the vial of Granocyte using the 19G needle. Shake gently until completely dissolved. Do not shake violently. Reconstituted solution for parenteral use appears transparent and free of particles Remove the required volume of reconstituted solution from the vial using the 19G needle Administer immediately by subcutaneous injection using the 26G needle.

Warnings and Precautions

Talk to your doctor or pharmacist before you start using: If you have ever had any medical conditions, especially allergies, infections, kidney or liver problems. If you have sickle cell disease or sickle cell trait, as Granocyte can potentially cause a sickle cell crisis. Please contact your doctor immediately if you experience during treatment with Granocyte: Pain in the upper left abdomen or left shoulder. These could be signs of an enlarged spleen or a possible rupture of the spleen. Swelling in your face or ankles, blood in your urine, or if your urine is brown or you notice that you urinate less than usual.

GRANOCYTE 33.6: A Boost to the Immune System

Granocyte 33,6, whose active ingredient is lenograstim, is a key drug in stimulating the body's defenses. It functions as a growth factor for colonies of granulocytes, a type of white blood cell crucial for the immune system. In essence, Granocyte signals the bone marrow to produce more neutrophils, which are the cells responsible for identifying and destroying bacteria and other infectious agents. By increasing the number of these cells, the drug strengthens the body's ability to fight infections more quickly and efficiently, which is vital for the patient's overall health.

Cancer Treatment Support

One of the most significant uses of Granocyte 33,6 is in the treatment of cancer patients receiving chemotherapy. These treatments, while essential for fighting cancer cells, often damage the bone marrow and cause a drastic decrease in white blood cell count, a condition known as neutropenia. Severe neutropenia leaves the patient extremely vulnerable to life-threatening infections. Granocyte helps shorten the duration of this neutropenia, allowing for faster recovery of neutrophil levels. By reducing the risk of infections, the drug makes it easier for patients to continue with their chemotherapy cycles as scheduled, improving the effectiveness of overall treatment.

Cell Mobilization for Transplantation

In addition to its use in neutropenia, Granocyte is used for the mobilization of hematopoietic progenitor cells from peripheral blood. This process involves stimulating the bone marrow to release these immature cells (capable of transforming into different blood cells) into the bloodstream, where they can be collected. This method is a modern and effective alternative to direct bone marrow collection. The collected cells can then be used in transplants, either for the patient themselves (autologous transplant) or for a recipient, helping to restore the blood-producing system after intensive treatment.